Antibiotic alternatives: ‘We kind of pride ourselves in my research group of doing the crazy stuff’

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As the world loses its upper hand in the antibiotic arms race, it raises the specter of un-treatable infections resulting from routine surgeries. But a Canadian scientist has discovered a surprising source of potential antibiotic options. Over the past few months, there’s been grim evidence of the march to a post-antibiotic world. Last week, for instance, U.S. researchers said they’d identified what could be the … Read More

Antibacterial Ingredients in Indoor Dust Could Contribute to Antibiotic Resistance

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To better understand the problem of antibiotic-resistant bacteria, researchers have been piecing together its contributing factors. Now in the ACS journal Environmental Science & Technology, scientists report for the first time a link between antimicrobial substances such as triclosan in indoor dust and levels of antibiotic-resistance genes, which can transfer from one bacterial cell to another. The overuse of antibiotics … Read More

Pets and Children are a Potential Source of Clostridium difficile in the Community

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Household transmission of Clostridium difficile to pets and children may be a source of community-associated C. difficile infections according to findings from a new study published today in Infection Control & Hospital Epidemiology. The study found that patients with this bacteria can colonize or infect household contacts following or during treatment for an infection. “C. difficile is primarily a healthcare-associated … Read More

New Zika Clone Could be New Model for Developing Vaccine

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Stopping the explosive spread of Zika virus – which can lead to birth defects in babies born to infected mothers – depends on genetic insights gleaned through new tools and models. Researchers at the National Institutes of Health recently cloned an epidemic strain of the virus, creating a model that can help biologists develop and test strategies for stopping the … Read More

Clinical Trial Will Examine Investigational Vaccine Against Mosquito-Borne Illness

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As world leaders increasingly recognize the Zika virus as an international public health threat, the Center for Vaccine Development at the University of Maryland School of Medicine’s Institute for Global Health has been chosen as one of three study sites in a human safety trial of a new Zika vaccine. The early-stage study will evaluate the experimental vaccine’s safety and … Read More

Glucose Transporters Blocked in Bacterial Meningitis

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Escherichia coli K1 (E. coli K1) continues to be a major threat to the health of young infants. Affecting the central nervous system, it causes neonatal meningitis by multiplying in immune cells, such as macrophages, and then disseminating into the bloodstream Meningitis can be caused by bacterial, fungal or viral pathogens. One hallmark of bacterial meningitis is reduced glucose levels … Read More

Public Health Officials Investigating Unique Case of Zika in Utah

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Utah health officials confirmed today a new case of Zika in Utah and have launched an investigation to determine how the person became infected. The new case is a family contact who helped care for the individual who died from unknown causes and who had been infected with Zika after traveling to an area with Zika. Laboratories at the Centers … Read More

Angina Drug Could Inform a New Strategy to Fight Cryptococcosis

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A drug more commonly used in the treatment of angina could be the focus of a new strategy in fighting the fatal fungal infection cryptococcosis. Researchers from the University of Birmingham found that the compound fendiline hydrochloride could be used to stimulate a patient’s own white blood cells to fight the disease more effectively, instead of trying to use drugs … Read More